A study of the prevalence of psoriasis in the city of Fallujah and its correlation with some immunological and hematological parameters
No Thumbnail Available
Date
2024-11-11
Journal Title
Journal ISSN
Volume Title
Publisher
Research Journal of Biotechnology
Abstract
Abstract
Psoriasis is a common, chronic inflammatory skin disease with associated systemic inflammation. This study was conducted to determine the prevalence of psoriasis in the city of Fallujah on 859 patients visiting dermatology physician and also to determine the effect of psoriasis on the levels of some hematological parameters including total and differential white blood cell count, red blood cell count, hemoglobin level, platelets count in 102 psoriatic patient and 62 people for control.
The study concluded presence of mild prevalence of cutaneous psoriasis among patients visiting dermatologist physicians in Fallujah city which was abundant mostly in young adults (21-30) years and elevated incidence in males. Some hematological markers could be considered as a tool for differentiating cutaneous psoriasis from other cutaneous infections and have correlations with PASI system of diagnosis. WBCs count was elevated in psoriasis. The most abundant types in psoriasis are neutrophils and lymphocytes and platelets would be lower in psoriatic patients in correlation with severity of the disease.
Description
Psoriasis is a chronic inflammatory skin disease often accompanied by systemic inflammation. This study aimed to determine the prevalence of psoriasis in Fallujah by analyzing data from 859 patients visiting a dermatology clinic. Additionally, it examined the effects of psoriasis on hematological parameters, including total and differential white blood cell (WBC) count, red blood cell (RBC) count, hemoglobin levels, and platelet count. The study involved 102 psoriasis patients and 62 healthy controls.
Findings indicated a mild prevalence of psoriasis among dermatology patients in Fallujah, with a higher incidence among young adults (21–30 years) and males. Certain hematological markers were identified as potential tools for distinguishing psoriasis from other skin infections. Notably, WBC counts were elevated in psoriasis patients, particularly neutrophils and lymphocytes, while platelet levels tended to decrease in correlation with disease severity. These hematological changes may have diagnostic and prognostic implications, especially about the Psoriasis Area and Severity Index (PASI).
Keywords
Citation
Jamal, A. R., Gatia, A. S. O., Bedwi, H. A., Khalil, I. A., & Adnan, M. R. (2024). A study of the prevalence of psoriasis in the city of Fallujah and its correlation with some immunological and hematological parameters. Research Journal of Biotechnology Vol, 19, 11.